Inadvertent intra-arterial promethazine injury

Gangrene of the hand and forearm after inadvertent intra-arterial injection of pyrazole. A case report.

A case of gangrene of the hand following inadvertent intra-arterial injection of a pyrazole derivative (Tomanol) is presented. Gangrene of the hand and superficial sloughing of the distal arm necessitated a forearm amputation. Because of the serious sequelae, precautions must be taken to avoid inadvertent intra-arterial injections and due consideration must be given to the anatomical variation ...

Ischemic Stroke and Seizure as Complication from Inadvertent Intra-Arterial TPN Infusion: A Case Report

PICC linesare increasingly common in the hospitalized patient. Catheter misplacement is a recognized complication of PICC insertion. This article describes a unique case of stroke accompanied by nonconvulsive status epilepticus (NCSE) as a result of total parenteral nutrition (TPN) continuously infusing from a peripherally inserted central catheter (PICC) in a patient's aorta. A 58 year old wom...

Intra-arterial transfusion in the treatment of severe injury.

Accidental intra-arterial injection.

Accidental intra-arterial injection of intramuscular antibiotic preparations is described in 3 cases in infants. In 2 benzathine penicillin was injected, and in 1 rolitetracycline. The clinical features are dominated by arteriolar obstruction which produces gangrene of the most severely affected limb. In addition, neuroloigcal involvement occurs when vessels to nerves or spinal cord are involve...

Preventing serious tissue injury with intravenous promethazine (phenergan).

Vol. 34 No. 4 • April 2009 • P&T® 175 Severe tissue damage can occur regardless of the route of parenteral administration, although IV and inadvertent intra-arterial or subcutaneous (SQ) administration results in more significant complications, including burning, erythema, pain, swelling, severe spasm of vessels, thrombophlebitis, venous thrombosis, phlebitis, nerve damage, paralysis, abscess, ...